Ubiquitin - proteasome pathway is a highly effective protein - degradation pathway in the eukaryotic cells.
泛素 - 蛋白酶體途徑是真核細胞內一種高效蛋白降解途徑.
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Skp 2 is an Fbp, which targets many ubiquitin - mediated degradation of G 1 - and S - phase regulators.
研究表明許多惡性腫瘤中存在著Skp2相關機制的異常, Skp2現已被認為是一種重要的癌基因.
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So abnormality of the ubiquitin - proteasome proteolytic pathway is closely related to many diseases, especially cancer.
泛素介導的蛋白質降解途徑的異常與許多疾病特別是腫瘤的發(fā)生密切相關.
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Conclusion: GFPu - 1 clonal cells may be a sensitive indicator for the function of the ubiquitin - proteasome system.
結論: GFPu -1 克隆細胞是一種反映UPS功能的敏感指標.
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The mRNA expression of ubiquitin in rat EDL muscle was determined by northern blot analysis.
應用northernblot方法測定伸指長肌組織泛素mRNA的 表達變化,分析骨骼肌蛋白降解與泛素mRNA表達的關系.
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